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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK8
All Species:
10.91
Human Site:
T291
Identified Species:
18.46
UniProt:
Q86SG6
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86SG6
NP_835464.1
692
74806
T291
S
N
T
G
S
R
T
T
S
V
R
C
R
G
I
Chimpanzee
Pan troglodytes
XP_511801
843
90571
T442
S
S
T
G
S
R
T
T
S
V
R
C
R
G
I
Rhesus Macaque
Macaca mulatta
XP_001106986
781
84378
T380
S
S
T
G
S
R
T
T
S
V
R
C
R
G
I
Dog
Lupus familis
XP_548291
727
78319
G319
G
P
P
M
A
P
G
G
S
T
G
S
R
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZR4
698
75246
S291
G
P
P
I
A
S
G
S
T
G
S
R
A
T
S
Rat
Rattus norvegicus
NP_001099274
698
75236
S291
G
T
P
M
A
P
G
S
T
G
S
R
A
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512532
832
89432
G275
G
R
G
G
S
R
V
G
S
A
R
T
W
G
A
Chicken
Gallus gallus
XP_415822
728
79098
R291
V
Q
T
V
T
H
S
R
T
G
G
R
V
S
S
Frog
Xenopus laevis
Q7ZZC8
944
104521
V316
K
K
P
R
T
G
T
V
T
E
A
P
I
A
V
Zebra Danio
Brachydanio rerio
Q90XC2
697
76523
R291
V
Q
A
G
P
H
G
R
P
G
G
W
I
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_490968
998
111830
I467
I
P
D
L
P
S
R
I
S
I
K
Q
V
A
L
Sea Urchin
Strong. purpuratus
XP_001201534
446
48490
P82
A
F
T
V
V
G
T
P
S
Y
I
S
P
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9CAU7
606
68016
N242
V
K
S
M
L
R
K
N
P
E
L
R
P
S
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48479
858
94329
W346
D
A
S
L
R
R
E
W
E
V
K
A
R
L
E
Conservation
Percent
Protein Identity:
100
75.4
87
88.8
N.A.
93.5
93.4
N.A.
68.7
76.9
24.7
73.8
N.A.
N.A.
N.A.
23.2
38.2
Protein Similarity:
100
76.9
87.8
91
N.A.
96.4
95.4
N.A.
74
85.1
39.5
85.2
N.A.
N.A.
N.A.
37.8
50.8
P-Site Identity:
100
93.3
93.3
13.3
N.A.
0
0
N.A.
40
6.6
6.6
6.6
N.A.
N.A.
N.A.
6.6
20
P-Site Similarity:
100
100
100
20
N.A.
20
20
N.A.
40
26.6
26.6
6.6
N.A.
N.A.
N.A.
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.2
N.A.
21.7
Protein Similarity:
N.A.
N.A.
N.A.
44
N.A.
37.1
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
22
0
0
0
0
8
8
8
15
15
22
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
22
0
0
0
% C
% Asp:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
8
15
0
0
0
8
8
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
29
0
8
36
0
15
29
15
0
29
22
0
0
29
0
% G
% His:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
8
0
0
0
8
0
8
8
0
15
0
22
% I
% Lys:
8
15
0
0
0
0
8
0
0
0
15
0
0
0
0
% K
% Leu:
0
0
0
15
8
0
0
0
0
0
8
0
0
8
15
% L
% Met:
0
0
0
22
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
22
29
0
15
15
0
8
15
0
0
8
15
0
0
% P
% Gln:
0
15
0
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
8
0
8
8
43
8
15
0
0
29
29
36
0
0
% R
% Ser:
22
15
15
0
29
15
8
15
50
0
15
15
0
22
29
% S
% Thr:
0
8
36
0
15
0
36
22
29
8
0
8
0
22
0
% T
% Val:
22
0
0
15
8
0
8
8
0
29
0
0
15
0
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
8
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _